Gordon Dougal -- Infrared Therapy


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**Gordon DOUGAL**

**Infrared Therapy**

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[**http://www.mailonsunday.co.uk/health/article-1034936/Dementia-patient-makes-amazing-progress-using-infrared-helmet.html**](http://www.mailonsunday.co.uk/health/article-1034936/Dementia-patient-makes-amazing-progress-using-infrared-helmet.html)  
**Thursday, July 17 2008**

Dementia
Patient makes 'amazing' progress after using infra-red
helmet
By **David Derbyshire** 

Two months ago Clem Fennell was fading fast.

The victim of an aggressive type of dementia, the
57-year-old businessmen was unable to answer the phone,
order a meal or string more than a couple of words together.

In desperation, his family agreed to try a revolutionary
new treatment - a bizarre-looking, experimental helmet
devised by a British GP that bathes the brain in infra-red
light twice a day.

To their astonishment, Mr Fennel began to make an
astonishing recovery in just three weeks.

Dr Gordon Dougal, a GP from County Durham, treated dementia
patient Clem Fennell with his infra-red device

"My husband, Clem, was fading away. It is as if he is back"
said his wife Vickey Fennell, 55. "His personality has
started to show again. We are absolutely thrilled."

While the helmet has yet to be proven in clinical trials,
the family say the effects of the 10 minute sessions are
incredible. Mr Fennell can now hold conversations and go
shopping unaccompanied.

The treatment is the brainchild of Dr Gordon Dougal, a
County Durham GP. He believes the device could eventually
help thousands of dementia patients.

"Potentially, this is hugely significant," said Dr Dougal,
who is based in Easington, County Durham and is a director
of Virulite, a medical research company.

Developed with Sunderland University, the helmet has 700
LED lights that penetrate the skull. They are thought to be
the right wavelength to stimulate the growth of brain cells,
slowing down the decline in memory and brain function and
reversing symptoms of dementia.

Clem Fennell - the head of a family engineering firm in
Cincinnati, Ohio - travelled to the UK after neurologists
told him nothing could stop the decline of his dementia. The
family's friends had seen a report about the helmet on CBS.

"Honestly I can tell you that within ten days, the
deterioration was stopped, then we started to see
improvements," said Mrs Fennell, from North Kentucky. "He
started to respond to people more quickly when they talked
to him."

Three weeks later, the father of two is still making
gradual improvements.

His daughter, 22-year-old Maggie said: "When we go to the
restaurant we usually have to order his meals for him, now
he can order for himself."

"Now we are okay about letting him go to the bank or
the  post office but he would not have been able to do
that three weeks ago.

Mr Fennell could hardly string two words together. But
since using the infra-red helmet, he can hold a
conversation.

"Dr Dougal has been a godsend to our family. There was
nothing anyone could do to help Clem until now."

It is too soon to say whether Dr Dougal's invention could
help other sufferers. The symptoms of Alzheimer's disease
and dementia can vary from day to day --- and relapses are
not unusual. And not all patients may benefit from the
treatment.

Dr Dougal stressed that a full, clinically controlled trial
would be needed  before his anti-dementia helmet could
be licensed for public use. A trial of 100 patients is
expected to start later this year.

"I made it clear to the Fennells that I didn't know for a
fact  whether it would work or not, but the results are
good," said Dr Dougal.

"He was monosyllabic when I first saw him, but if I ring up
now he will answer  the phone. He didn't have the
verbal skills to do that three weeks ago."

The Fennells have been told they can take the prototype
helmet back to the US  with them so they can continue
the treatment at home.

Commercial versions of the helmet will include 700 LEDs and
cost around GBP10,000.

The Alzheimers Society said: "A treatment that reverses
the effects of dementia rather than just temporarily halting
its symptoms could change the lives of the hundreds of
thousands of people who live with this devastating
condition.

Non-thermal near infra-red treatment for people with
dementia is a potentially interesting technique. We look
forward to further research to determine whether it could
help improve cognition in humans. Only then can we begin to
investigate whether near infra-red could benefit people with
dementia.

One in three people will end their lives with a form of
dementia. Around 700,000 suffer from dementia - with more
than half having Alzheimer's disease.

![](dougal.jpg)

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[**http://www.medicalnewstoday.com/articles/95334.php**](http://www.medicalnewstoday.com/articles/95334.php)  
28 Jan 2008

**Infra Red Helmet For Reversing Early
Alzheimer's To Be Tested**

 by **Catharine Paddock**

Medical experts in the North-East of England,
UK, have found that safe exposure to infra-red light improves
learning and cognitive functioning in the brain, and they are
going to test the method by getting Alzheimer's patients to
wear an infra-red "helmet" for a short time every day.

The scientists believe the method can turn back
the brain's biological clock and reverse some of the early
stage damage typical of dementia and memory loss.

Dr Gordon Dougal, a director of medical research
company Virulite, in County Durham, came up with the idea of
using infra red to repair damage to human brain cells after
successfully developing a cold sore machine that boosts the
body's own ability to fight the virus instead of attacking it
directly.

The idea has been tested independently by
researchers at the University of Sunderland, who showed that
low power infra-red light (1072nm) improved learning.

Human trials on patients with diseases like
Alzheimer's are due to start. The low level of infra-red light
is the same as that which occurs in natural sunlight and is
completely safe, said the researchers. The level of exposure
is the same as that used in the cold sore machines, which have
now been approved for prescription on the NHS.

The idea is that patients could use an infra red
helmet for ten minutes a day in their own home and notice a
significant improvement in the space of four weeks.

The researchers are hoping to start testing the
idea on patients with Alzheimer's and other degenerative brain
diseases this summer.

It is possible that the method not only halts
but actually reverses the effects of dementia, said Dougal,
who went so far as to suggest that one day the method might
even be used to change the rate at which our bodies age.

"As we get older, cells stop repairing
themselves and we age because our cells lose the desire to
regenerate and repair themselves," said Dougal.

"This ultimately results in cell death and
decline of the organ functions, for the brain resulting in
memory decay and deterioration in general intellectual
performance," he added.

"But what if there was a technology that told
the cells to repair themselves and that technology was
something as simple as a specific wavelength of light? Near
infrared light penetrates human tissues relatively well, even
penetrating the human skull, just as sunlight passes through
frosted glass," explained Dougal.

Neuroscientists at the University of Sunderland,
Drs Dr Abdel Ennaceur and Paul Chazot carried out the
independent research that confirmed Dougal's findings. Chazot
said:

"The treatment can indeed improve learning
ability. The results are completely new this has never been
looked at before."

"Dr Dougal's treatment might have some potential
in improving learning in a human situation by delivering infra
red through the thinnest parts of the skull to get maximum
access to the brain," he added.

Click here for source of this news item and a
photo of the research team with the "helmet" (University of
Sunderland).

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**Patents**

**A method of cosmetically treating skin using
electromagnetic radiation with a wavelength between 900nm
and 1500nm**   
**GB2415387**   
2005-12-28

![](gb1.jpg)  ![](gb2.jpg)

**Abstract** --- A method of cosmetically
treating a superficial area of mammalian skin by irradiating
the skin with a source of divergent electromagnetic radiation
of between 900nm to 1500nm and the use of electromagnetic
radiation of the same wavelengths. The cosmetic treatment
includes reducing or alleviating or removing or diminishing
wrinkles or fine lines, rejuvenating skin, retarding or
reversing visible signs of aging, improving skin elasticity,
tone, texture and appearance and beautifying facial, breast,
arm, buttock, thigh, stomach or neck skin. Also disclosed is
an ex-vivo method of improving immune cell viability
comprising exposing peripheral blood mononuclear cells to
divergent electromagnetic radiation of narrow bandwidth
centred around a wavelength of 1072nm.

**USE OF ELECTROMAGNETIC RADIATION IN THE
TREATMENT OF SENSORY ORGANS**   
**EP1896131**   
2008-03-12

![](ep1.jpg)

**Abstract** --- A method of using and
devices for delivering electromagnetic radiation of a selected
wavelength for the treatment of conditions pertaining to
cephalic sensory organs, in particular to treating conditions
of the eye (ocular conditions) and conditions pertaining to
the ear (otic conditions). The invention is in particular for
the treatment of organelles associated with the acoustic and
optic nerves and more particularly for the treatment of age
related degeneration of such organelles. The invention also
provides devices for treating ocular and otic conditions.   
Also published as: WO2006134339 (A1) // EP1896131 (A0)
//  CA2610247 (A1) // AU2006258840 (A1)

**Electromagnetic Radiation Therapy**   
**US2007129778**   
2007-06-07   
Abstract -- An electromagnetic radiation therapy system
comprises means for emitting divergent electromagnetic
radiation having a wavelength between 950 and 1500 nm and
being capable of producing, at the site being treated, a
radiation intensity of at least 50 muWatts/cm<2>. Also
disclosed are the use of the system for treating various
conditions and the method of applying the treatment.   
Also published as:  WO9919024 (A1) // EP1021223 (A1)
//  US2005234383 (A1) // GB2344532 (A) // EP1021223 (A0)

**ELECTROMAGNETIC RADIATION THERAPY**   
**WO0035534**   
2000-06-22   
Abstract -- The present invention discloses an apparatus for
emitting electromagnetic radiation of between 980 and 1350 nm
to skin covering skull, temple regions and/or frontal lobes of
an individual's head, the apparatus comprising means for
emitting electromagnetic radiation and being capable of
producing, at the site being treated, a radiation intensity of
at least 15 mWatts/cm^2 and up to 10 Watts/cm^2.

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**United States Patent
Application   20070129778**

**Electromagnetic Radiation Therapy**

Dougal; Gordon Rex Paterson   
June 7, 2007

**Abstract --** An electromagnetic radiation
therapy system comprises means for emitting divergent
electromagnetic radiation having a wavelength between 950 and
1500 nm and being capable of producing, at the site being
treated, a radiation intensity of at least 50
.mu.Watts/cm.sup.2. Also disclosed are the use of the system
for treating various conditions and the method of applying the
treatment.

Inventors:  Dougal; Gordon Rex Paterson;
(Durham, GB)   
Correspondence Name and Address:   
MYERS BIGEL SIBLEY & SAJOVEC : PO BOX 37428, RALEIGH NC
27627 US

U.S. Current Class:  607/88   
U.S. Class at Publication:  607/088   
Intern'l Class:  A61N 5/06 20060101 A61N005/06

**Description**

**RELATED APPLICATIONS**

[0001] This is a continuation application of and
claims the benefit of priority from co-pending U.S. patent
application No. 11/155,431 filed Jun. 17, 2005, which is a
continuation application of U.S. patent application Ser. No.
09/529,210, filed Jul. 24, 2000, which is a National Phase
application of International Application Serial No.
PCT/GB98/030373, filed Oct. 12, 1998 and published as PCT
Publication No. WO 99/19024, which claims priority from Great
Britain Patent Application Serial No. 9721506.5 filed Oct. 10,
1997, and Great Britain Patent Application Serial No.
9727441.9, filed Dec. 31, 1997, the disclosures of which are
incorporated herein by reference in their entireties.

**FIELD OF THE INVENTION**

[0002] This invention relates to an apparatus
producing, and a method of therapy using, electromagnetic
radiation for the treatment of diseases and for the
maintenance or improvement of organs or body tissues,
including muscles. The invention may be used in connection
with the cure or alleviation of a variety of diseases
including infectious diseases and pathological processes
including those caused by viruses and bacteria.

[0003] By way of example, the invention may be
used in connection with diseases caused by the herpes virus
which is known to be responsible for a number of common
ailments including corneal dendritic ulcers, genital herpes,
herpes labialis (cold sores), herpes zoster (shingles) and
herpes stomatitis. These infections tend to be recurrent and
are not cured by existing, medically accepted treatments.

**BACKGROUND OF THE INVENTION**

[0004] Current medically accepted methods of
treating infections caused by the herpes virus are
chemotherapeutic agents which are applied topically, injected
or taken orally. Such treatment can often deal with the
immediate infection but does not prevent a recurrence of the
infection at a later date after the treatment has ceased.

[0005] It has been known for several decades
that the use of light can give a positive therapeutic effect
in the treatment of a wide spectrum of diseases. In the 1960's
the use of narrow wavelength light was investigated in in
vivo/in vitro experiments. It was found that light of
wavelength greater than 440 nm did not work. Further
investigations were carried out with light having a wavelength
of from 300 to 350 nm (UV light) but it was found that
infection was exacerbated/promoted rather than
ameliorated/eliminated. Some attempts have been made to treat
individuals affected with the herpes virus by treatment with
light of the wavelength 660 nm, as described in U.S. Pat. No.
5,500,009. However, the present inventor was unable to achieve
a significant clinical outcome or benefit at that wavelength.

[0006] Additionally, it is known from the prior
art to use a laser to produce coherent radiation and to focus
it on the area to be treated. Nd YAG laser treatment at a
fundamental wavelength of 1064 nm is associated with decreased
pain, scarring and improved healing (U.S. Pat. No. 5,445,146).
Additionally it has been reported that diodes emitting light
at the red wavelength, 940.+-.25 nm can be used to treat a
range of essentially musculoskeletal ailments (U.S. Pat. No.
5,259,380). However there is no indication that light of a
wavelength above this would be of any therapeutic use.

[0007] It has now been surprisingly established
that low intensity electromagnetic radiation of small
bandwidth is effective in the treatment of infectious
diseases, inflammatory-type diseases and other conditions,
including the alleviation of pain. It is postulated that the
way in which the electromagnetic radiation effects its action
is by way of energy transmission through cellular
components/organelles.

[0008] A water molecule that has a range of
electromagnetic radiation wavelengths passed through it will
produce several transmission peaks. These transmission peaks
are associated with the preferred therapeutic electromagnetic
radiation wavelength range of the invention and thus implies a
role for the water molecule in the general mechanism of
action.

**STATEMENTS OF THE INVENTION**

[0009] According to the present invention there
is provided an electromagnetic radiation therapy system
comprising means for emitting divergent electromagnetic
radiation between 980 and 1500 nm and being capable of
producing, at the site being treated, a radiation intensity of
at least 50 .mu.Watts/cm.sup.2 and up to 2 Watts/cm.sup.2.

[0010] Reference herein to a site being treated
is intended to include, without limitation, the skin or
musculature or internal organ of a human or animal subject.

[0011] Preferably the wavelength of the
electromagnetic radiation is in the range 980 nm-1300 nm. A
particularly preferred wavelength is at, or about, 1072 nm. A
yet further particularly preferred wavelength is at, or about,
1268 nm.

[0012] Our studies have shown that the
wavelength centred around 1072 nm is particularly effective at
treating herpetic and bacterial infections, alleviating acute
pain and in treating eye conditions, whilst the wavelength
centred around 1268 nm is particularly effective at providing
pain relief from deep muscle injury. It is of note that these
two preferred wavelengths correspond to the peak emission
wavelengths of a water molecule light transmission profile and
thus we believe that the mechanism of action is related to
water and possibly cell membranes.

[0013] By divergent it meant that the
electromagnetic radiation emitted from the system of the
invention has a divergent half angle of at least 5.degree..
Preferably divergence of the electromagnetic radiation is in
the range 15.degree. to 45.degree. half angled divergent.

[0014] Preferably the electromagnetic radiation
is continuous or pulsed.

[0015] Preferably when the electromagnetic
radiation is continuous the intensity is at least 50
.mu.Watts/cm.sup.2 for treatment of eyes and mucous membranes,
and more preferably is at least 500 .mu.Watts/cm.sup.2 for
treatment of skin and up to 2 Watts/cm.sup.2.

[0016] Preferably when the electromagnetic
radiation is pulsed the intensity is at least 50
.mu.Watts/cm.sup.2 peak power for treatment of eyes and mucous
membranes, and more preferably is at least 500 .mu.Watts/cm
peak power for treatment of skin and the average power is up
to 2 Watts/cm.sup.2. The average power is the peak power
multiplied by the proportion of the total time that the
radiation is applied. For instance if the peak power is 500
.mu.Watts/cm.sup.2 and is pulsed for 10 .mu.seconds at a
frequency of 600 Hz then the average power is 30
.mu.Watts/cm.sup.2.

[0017] Preferably when the electromagnetic
radiation is pulsed the average power of the intensity is in
the region of 50-100 .mu.Watts/cm.sup.2.

[0018] We have found that the power may suitably
range from 500 .mu.Watts/cm.sup.2 peak to 2 Watts/cm.sup.2
continuous or peak power when applied to the skin. In the
instance of applying electromagnetic radiation therapy to the
eye or mucous membrane, powers as low as 50 .mu.Watts/cm.sup.2
continuous or pulsed are found to be beneficial. Typically 10
mWatts/cm.sup.2 are used on skin but this value is dependent
on how fat or muscular the subject is and thus how deep the
tissue/area/organ to be treated may lie beneath the skin
surface. Typically radiation of the intensity 5
mWatts/cm.sup.2 is used on mucous membranes.

[0019] Preferably when the electromagnetic
radiation is pulsed it is applied for pulse duration periods
of at least 10-15 .mu.seconds and more preferably is applied
at a frequency/repetition rate in the range 480-800 Hz. More
preferably still, the frequency/repetition rate is at, or
about, 600 Hz.

[0020] Our studies have shown that the
electromagnetic radiation can be either coherent or
non-coherent the clinical outcomes are not affected by this
parameter.

[0021] Preferably the electromagnetic radiation
is applied to the affected area for at least 30 seconds and
upto a few minutes. A typical exposure time for the skin or
eye is in the region of 3 minutes, however for tissues well
below the skin surface this time is increased according to the
individuals fat/muscle layer depth and exposure could be up to
10 minutes.

[0022] It should be appreciated that the power
source emitting the electromagnetic radiation will have to
produce more than the required intensity for the clinical
effect since we have shown that approximately 99% of the
applied therapeutic amount of light is lost across the skin
surface during treatment. Thus the intensity of applied
radiation will have to be corrected for when carrying out a
treatment.

[0023] Our studies have shown that the first
clinical effects can be detected following 30 seconds of
treatment for herpetic infections and that the majority of
immediate clinical effects are experienced following 90
seconds of treatment. However certain tissues are more
sensitive, for example the mucous membranes are exposed to the
dosing regimen for approximately 30 seconds and immediate
clinical effects are noted after only 3 seconds of treatment.

[0024] From the foregoing it is understood that
the electromagnetic radiation may be directed to the target
site either continuously or in a switched (pulsed) manner. The
main benefit of switching enables power conservation and
facilities much higher peak power output, thereby improving
clinical response.

[0025] Preferably, electromagnetic radiation
therapy system also includes means for reducing the amount of
ambient radiation which impinges on the site of infection. The
presence of ultraviolet light and violet light as in sunlight
exacerbates herpetic conditions and it is preferred to exclude
wavelengths below 400 nm. More preferably, wavelengths below
500 nm are excluded.

[0026] Preferably the system further includes
means for fixing the intensity of the radiation within a
pre-determined range. The radiation output may be monitored
with a visible display indicating correct function of the
device both for intensity and wavelength.

[0027] Preferably the system further includes
means for controlling the duration of the application of the
radiation. Accordingly, the present invention is concerned
with the use of electromagnetic radiation having a wavelength
in the range from visible to infra red and applied at a low
intensity such that no thermal damage is caused to any human
or animal tissues.

[0028] In the case where the system is to be
used in such a way that radiation will be caused to enter the
eye, it is preferred that the power intensity does not exceed
100 mWatts/cm.sup.2. Otherwise, the power intensity may be
higher and can suitably be delivered in pulsed form, thereby
obtaining several watts of momentary power output, allowing
good penetration of tissue and substantial systemic effect.

[0029] The radiation producing means are
preferably solid state light emitting devices, more preferably
solid state light emitting diodes or gas discharge devices.
The radiation from such devices can be electrically operated
or the radiation can be delivered to an applicator via a
fibre-optic delivery system.

[0030] Preferably, the radiation emitter
includes a PN junction arranged to emit radiation with a
wavelength centring at or about 1072 nm or at or about 1268
nm. A single light diode assembly may include a plurality of
orientated junctions.

[0031] Infrared emitting diodes may be arranged
not only to emit radiation at a specific frequency but also to
emit a high intensity divergent beam.

[0032] A gas discharge device may include a
mixture of gases which will give an output at the desired
wavelength, for instance, 1072 nm.

[0033] Another preferred radiation producing
means is a laser diode device, an example being a laser diode
emitting light at a frequency of 1064 nm. Such a light
emitting means is of low power intensity having a divergent
beam and not giving rise to thermal damage. It may be used to
treat many conditions, including pain relief.

[0034] The present invention also provides the
use of divergent electromagnetic radiation having a wavelength
of between 980 and 1500 nm and an intensity of at least 50
.mu.Watts/cm.sup.2 and up to 2 Watts/cm.sup.2 to treat an area
of biological tissue of a living human or animal subject.

[0035] Preferably the electromagnetic radiation
as produced by the system of the invention provides for
treating conditions such as, without limitation, herpetic
infections, bacterial and/or viral infections of the skin or
upper respiratory tract, ophthalmic conditions such as "dry
eye syndrome", caustic injuries, musculoskeletal conditions,
inflammatory conditions such as rheumatoid arthritis and
malignancies, reduction of scarring, promotion of wound
healing, sports performance and providing acute and chronic
pain relief.

[0036] The use of restricted bandwidth radiation
can enhance the immune system as a result of which the body is
able to combat infections, such as the herpes virus.

[0037] Although reference has been made to
infections caused by the herpes virus, the present invention
is not limited to such infections. It is applicable to other
infections caused by all viruses including HIV, common cold
and influenza viruses.

[0038] The present invention also provides a
method of treating an area of biological tissue of a living
human or animal subject comprising applying to said area
divergent electromagnetic radiation having a wavelength of
between 980 and 1500 nm at an intensity of at least 50
.mu.Watts/cm.sup.2 and up to 2 Watts/cm.sup.2.

[0039] Preferably, the area to be treated is
irradiated so that the affected tissue receives at least
50-500 .mu.Watts/cm.sup.2 peak power of radiant energy,
depending on the tissue to be treated. A factor here is the
period of irradiation and, preferably, the period should be at
least a specified minimum of 10-15 .mu.seconds at a repetition
rate/frequency of 450-800 Hz and preferably for at least 30
seconds duration.

**BRIEF DESCRIPTION OF THE DRAWINGS**

[0040] Embodiments of the invention will now be
described, by way of examples only, and with reference to the
accompanying drawings, in which:

[0041] FIGS. 1 to 4 are a view with cover
removed, side view, under view and front view respectively of
a first embodiment in accordance with the present invention;

[0042] FIGS. 5 to 7 are a front view, top view
and under view of a second embodiment in accordance with the
present invention;

[0043] FIGS. 8 to 10 are a back view, top view
and a side view of a third embodiment of the present
invention;

[0044] FIGS. 11 and 12 are a side view and a
view from the right (as seen in FIG. 11) of a fourth
embodiment in accordance with the present invention; and

[0045] FIGS. 13 and 14 show further embodiments
of the present invention.

**DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS**

[0046] Referring to FIGS. 1 to 4, a first
embodiment in accordance with the present invention includes a
hand held divergent narrow wavelength radiation source 4 with
a built in timer and ambient radiation detector. A single
wavelength is used at any one time, preferably in the infrared
spectrum. However, the effective wavelengths, which may be
covered by such a device, extend from the visible spectrum to
the infrared. In another embodiment of the invention, two
wavelengths are used, one that is visible and the other that
is invisible, particularly in the case where the optimal
wavelength is in the infrared.

[0047] Radiation source 4 includes an elongate,
rectangular cross-section hollow body with one end 8 being
transparent to light. The radiation source includes an array
of light emitting diodes 2 mounted close to transparent end 8.
Power is delivered to devices 2 by means of batteries 3
located within hollow 3 of the body 4.

[0048] The radiation source is provided with two
On/Off switches 5, which may be actuated to initiate the
operation of the internal electronics. Both buttons 5 have to
be pressed simultaneously in order to operate the device
correctly, thereby preventing inadvertent use of the device.
Close to the end opposite transparent end 8 is a utility hole
6 which allows the radiation source to be hung up or attached
to another article such as a bunch of keys.

[0049] The radiation source is provided with
control electronics, which limit the time that the radiation
source is on and then automatically switches off the radiation
source. The control electronics monitor the ambient radiation
and, in the event that the ambient radiation is of an
intensity that would interfere with the therapeutic effect of
the radiation source, an alarm buzzer (not shown) sounds. The
radiation emitting devices 2 and their location and
arrangement within the radiation source are such that the
radiation emitted from the radiation source is in the form of
a divergent light beam. Flange 1 restricts the ambient
radiation incident on the area whilst being treated.

[0050] The radiation therapy system of the
present invention could be adapted to be portable and for use
by those individuals wishing to have their own self-contained
and battery operated devices. Additionally it could be adapted
so that during use an animal or human appendage could be
located within a hollow body 3 to receive radiation emitted
therefrom. This particular modification is particularly suited
to treatment of genital herpes around the scrotal sac and/or
penis.

[0051] Referring to FIGS. 5 to 7 of the
accompanying drawings, a second embodiment in accordance with
the present invention is in the form of a multi-panel narrow
wavelength radiation source. In this case, a plurality of
panels A are mounted in a side by side relationship on hinges
7 and 7A which, in turn, are connected to a stand 9 by means
of arms 10 and 10A. The arrangement is such that the panels
can move relative to each other and the stand can be adjusted
to alter the direction of illumination. The stand either
extends from the floor or is attached to a chair or bed.

[0052] The front wall of each panel A is
transparent and, mounted below the front wall, is an array of
radiation emitting devices 2.

[0053] As with the earlier above described
embodiments this embodiment of the invention includes control
electronics to limit the time of the application of the
radiation and to monitor the ambient radiation and provide an
alarm when the threshold value of the ambient radiation is
exceeded.

[0054] Referring to FIGS. 8 to 10 of the
drawings, a third embodiment in accordance with the present
invention is in the form of a narrow wavelength radiation
source with adjustable headgear.

[0055] Flange 1 excludes ambient light if the
device is in contact with the body.

[0056] The radiation source is, in use, located
on the operator's head by a band or helmet B and includes two
panels 11A and 11B of radiation emitting devices, panels 11A
and 11B being separated by an intervening notch 13. These
radiation panels 11A and 11B can be used either simultaneously
or separately, there being provided a switch (not shown) to
direct electrical power to one or both of panels.

[0057] The radiation panels 11A and 11B are held
close to the eyes by adjustable control elements 12A and 12B.

[0058] The radiation source is provided with
control electronics 4, which limit the time of application of
the photons to the affected site and also automatically switch
off the radiation at the end of the application period. As
before the control electronics monitor the ambient radiation
and provide an alarm when the threshold level is exceeded.

[0059] Referring to FIGS. 11 and 12 of the
accompanying drawings, a fourth embodiment of the present
invention is in the form of a narrow or restricted bandwidth
radiation source for delivery of photons to an orifice. In
this case the body of the radiation source includes an
elongate cylindrical portion 15 having at one end a flange 4
whose shape is indicated in FIG. 12. At its other end,
elongate portion 15 is hemispherical 15A. Radiation emitting
devices are located both in the elongate portion 15 and the
flange 16 and this radiation source can be used to deliver
photons to any orifice in the human/animal body, for instance,
the vagina, anus, oro and nasopharynx and buccal cavity. The
radiation source may be provided in different sizes according
to the size of the orifice into which it is to be inserted.

[0060] Control electronics limit the time of
irradiation and monitor the ambient radiation, as with the
previously described embodiments of the invention.

[0061] FIGS. 13 and 14 illustrate devices useful
in the treatment of the common cold and acne.

[0062] The common cold is caused by a viral
infection of the upper respiratory tract. The viral particles
are almost exclusively found in the pharynx, sinuses and nasal
passages.

[0063] The device is a radiation emitting
apparatus, which delivers a narrow bandwidth radiation, which,
is of a wavelength, that will penetrate the superficial skin
and penetrate the underlying tissue to sufficient extent to
generate a therapeutic effect.

[0064] The device in FIG. 14 is flexible and is
placed against the patient's face whilst he is lying supine.
Notch 18 provides an aperture for the patient's eyes. Panel A
provides treatment for the frontal sinuses. Panel A' provides
treatment for the maxillary sinuses and nose, and the
intervening bridge 17 provides treatment for ethmoid sinuses
and nose.

[0065] The device in FIG. 13 is a flexible
radiation emitting apparatus, which is placed against the
patient's neck so that the points 20 approximate the base of
the patient's ears. This apparatus delivers radiation for
therapeutic effect to the patients larynx, oropharynx and
laryngopharynx. Depression 19 fits underneath the patient's
chin.

[0066] Devices for treating acne are as shown in
FIGS. 13 and 14 and comprise several panels of variable shape
and size. All the panels have a radiation emitting device 2
and are flexible to enable the panel to follow the contour of
the face and neck. Panels A and A' (FIG. 13) are applied to
the inferior aspect of the chin and the neck respectively.

[0067] Panels A and A' in the FIG. 14 device are
applied to the face so that notch 1 enables the patient to see
whilst being treated. Bridge 17 treats the bridge of the nose
and extension 2 the cheeks. Notch 21 rests on the tip of the
nose allowing the patient to breathe comfortably during
treatment. Panel A' is used to treat the chin area and the
area at notch 22 adjacent to the mouth.

[0068] Where the chest and/or back is involved a
larger version of panel A would be used as in FIG. 5.

[0069] Due to the superficial nature of the
pathology ambient radiation is of significance and an ambient
radiation detector is utilised.

[0070] Treatment time is at most 10 minutes but
typically 5 minutes.

[0071] It should be appreciated that two or more
of the above-described devices can be used in conjunction with
one another. An example is in the treatment of paediatric
herpetic stomatitis where the device for delivery of radiation
to an orifice could be used in conjunction with the multipanel
device to ensure adequate delivery of the radiation system.

[0072] The application of radiation in the
manner described appears to give the patient immediate (within
6 minutes) relief from any pain which is chemically mediated
irrespective of the inflammatory condition causing it i.e. it
gives pain relief in conditions other than those caused by
viral infections. It does not affect the conduction of pain
impulses as in local anaesthetics.

Experimental Results

[0073] Examples of the invention will now be
described with reference to the treatment of particular
conditions.

**Herpes**

[0074] The radiation-emitting surface was placed
against the cold sore for at least 90 seconds, typically 4
minutes. The environmental conditions must be such that the
ambient radiation to the cold sore must be decreased below
acceptable levels. This can be achieved either by switching
the radiation off or designing the device with a flange around
the outside, diminishing the ultraviolet light to the area.
Treatment is only once a day. One treatment may be all that is
necessary however, in view of the fact that this also enhances
wound regeneration and the wound regenerative effect only
lasts 24 hours, daily treatments would improve clinical
response. Various wavelengths were evaluated using a double
blind control trial, Zovirax.RTM.) being given to the control
patients. The average time for patient to be treated with 660
nm radiation took 7.5 days. The average time for a patient to
be treated with 1072 nm radiation was 3 days if lesion was
already present. However it was less than 12 hours if the
patient only has a tingling sensation.

[0075] 99.5% of patients abort their attack if
they are treated within the tingling period using 1072 nm
radiation. The cure rate of the patients receiving radiation
treatment was total, in that none had a recurrence of their
cold sores at the site treated. However 20% of the acyclovir
treated group had recurrence at the site of treatment.

[0076] The number in the trial was 300.

[0077] A further study was conducted in a double
blind protocol comparing radiation treatment to acyclovir. The
group receiving radiation therapy had cold sores that healed
within 4.7 days and the group receiving acyclovir had cold
sores that healed within 4.7 days. Statistical analysis
resulted in a p value of 0.027, which was statistically
significant.

[0078] Please refer to the table below for
further details. TABLE-US-00001 Number of Mean Time to
Treatment Patients Healing (days) Placebo radiation plus
acyclovir 14 6.9 Active radiation 15 4.7 Active radiation plus
placebo cream 16 6.7 Acyclovir 18 8.5 Red Light 20 7.5

**Genital herpes**

[0079] Again the applicator was required to
follow the contours of the genitals and for a woman the cervix
and posterior fornix was treated simultaneously with vagina
and perineum. The treatment period is only 4 minutes. Due to
the shape of the device, ambient radiation is excluded from
the treatment area, and darkened room is not necessary.

[0080] A total of eight patients have been
treated, all of who have reported a shorter duration of their
recurrent attacks of genital herpes. In addition, after one
year of treatment, for each attack, all patients have been
free from recurrence for the last 6 months, whereas they
typically had an attack per month.

**Shingles**

[0081] The radiation panel was applied to the
area that is infected, for periods of 4 minutes. If the panel
is applied to the actual skin surface and the panel is
optically opaque it will occlude the ambient radiation from
the area and hence allow treatment to proceed successfully.
The only exception where a darkened room is essential is for
the treatment of ophthalmic conditions when one cannot have
the radiation-emitting surface close to the eye because of the
generation of heat. The generation of heat in association with
ophthalmic conditions is contraindicated. A helmet was used
with an ambient radiation detector with alarm so that the
radiation can be delivered to the orbital region. Again the
treatment period was 4 minutes. Generally ophthalmic
conditions are treated on a daily basis. However, ophthalmic
herpes can be treated once every three days to achieve a
positive result.

[0082] Four patients have been treated; all of
who had significantly shortened healing periods and decreased
incidence or recurrence.

**The Common Cold**

[0083] The patient was reclined on a bed,
preferably in subdued lighting, but this is not essential. The
device was placed against the skin ensuring that the frontal,
ethmoidal and maxillary sinuses are covered. Another panel was
placed again the neck, ensuring that the device goes as high
as the angle of the jaw to enable treatment of the pharynx and
larynx areas. The treatment cycle is at least 4 minutes. After
that has been completed an oral device was used which is very
similar to the vaginal applicator without the flange. The
device was inserted into the patient's mouth. The treatment
period was again for 4 minutes. This applicator has a
disposable outer skin, which is changed with each patient. The
applicator will treat the soft palate and the back of the oral
pharynx and the top of the nasopharynx where the surface
applicator would not achieve acceptable penetration levels.
Using this protocol alleviation of the pain associated with
pharyngitis was achieved immediately, i.e. within 90 seconds,
and the symptoms associated with oral pharyngitis have been
alleviated within six hours.

[0084] Ten patients have been treated. Of note
is that unrestricted light can be applied to the pharynx with
immediate relief of symptoms, however for improved efficacy,
light of the wavelength 1072 nm is required to be applied to
the face and sinuses. We noted that in all cases the sore
throat was improved immediately and symptoms of congestion and
flu-like illness were alleviated in 4-6 hours.

**Acne**

[0085] Using the same applicator adolescent acne
can be treated by the simple addition of a chin extension. The
treatment time is 4 minutes. Ambient light is important but
not in as much as the applicator will have an opaque surface
so therefore it will be sheer proximity to the skin reduce
ambient light to the skin. Applications should initially be
every two to three days and maintenance would be perhaps once
a week.

[0086] Twelve patients have successfully been
treated with light of the light therapy system. Results
indicate that if 950 nm 5 mm diodes were used there was a
marked exacerbation of the disease process, however when using
950 nm 8 mm diodes there was a slight increase in inflammation
but an overall improvement. The use of restricted radiation
resulted in a rapid resolution of acne over 7 days. Daily
treatment enhanced clinical results. Once a clinical result
was achieved, the regimen was maintained for 1-2 treatments
per week for a satisfactory outcome.

**Musculoskeletal Disorders**

[0087] Treatment of musculoskeletal disorders
such as tennis elbow gout, muscle injuries and knee injuries.
The application time again is only 4 minutes. The radiation is
directed over the affected area and gentle pressure is
applied. Once the treatment is complete the patient feels
immediate pain relief and improved joint movement. Muscle
stiffness is greatly improved. This is a distinct advantage in
the treatment of gout since this can be an extremely painful
condition. The treatment could be repeated after 24 hours.
Generally speaking treating prior the 24 hours is not
indicated, as there is no additional clinical benefit.

**Post-Operative Wounds**

[0088] 24 hours after an operation, a 4-minute
treatment period reduces pain for 6-8 hours and this was
repeated three to four times a day to enhance would healing.
The treatment may be used on a daily basis with or without the
pain for post-operative wounds.

[0089] Seven volunteers, all of whom had minor
surgery found decreased scar formation if the area of surgical
incision was treated daily for 10 days commencing on the day
of surgery. Thus it is envisaged that the present invention
has applications in the treatment of keloids, burns and
cosmetic surgery.

**Connective Tissue Diseases**

[0090] Rheumatoid arthritis is an example of
this group of conditions. The painful areas are treated in a
device which comprises one fixed panel in which the hands are
placed on and a flexi panel which is placed over the top of
the hands applying gentle pressure to aid additional
penetration of the skin. The treatment time is 4 minutes.
Ambient radiation does not appear to be a significant factor
in the treatment of rheumatoid arthritis. Part of the
treatment protocol can also be in the treatment of thymus,
liver and regional lymph nodes, which are all associated with
antigen recognition. Again treatment time is 4 minutes. The
thymus, lymph nodes, liver and spleen may be treated once a
week, whereas the hands may be treated initially once a week.
However, during an acute exacerbation they can be treated
daily. If treated more than once daily there appears to be no
advantage.

[0091] A small trial involving eight patients in
the Rheumatology Clinic resulted in the findings that those
receiving placebo radiation treatment felt more relief than
those patients receiving active 950 nm radiation. However,
when using radiation in the restricted wavelength according to
the present invention, all ten patients reported a clinical
benefit compared to the placebo treatment. In addition we
found that if the thymus and other aspects of the
reticuloendothelial system were treated with the restricted
radiation the patients experienced an overall cessation of
their arthralgia and myalgia.

**Malignancy**

[0092] The area of the tumour is treated
together with treatment to the antigen recognition centres
such as thymus, spleen, liver and lymph nodes. Daily whole
body treatments may be carried out.

**Bacterial Infections**

[0093] A number of diverse minor bacterial
infections have been treated successfully in 35 patients. In
all cases the infection had been present for at least three
days and was considered to be worsening daily. At the time of
treatment each patient would have ordinarily been prescribed
an oral antibiotic. In 70% of cases the infection was
resolving 6 hours after treatment and was completely better
within one day. In the remaining 30% of cases the infection
had improved considerably within one day and following a
second radiation treatment, the infection was gone by the
second day. Of clinical note was the observation that in the
Caucasians treated there was a significant decrease in
superficial scar tissue at the site of assault. As previously
noted, the 8 mm 950 nm diode unrestricted radiation source was
effective but not as effective as the restricted radiation of
1072 nm of the present invention.

**Sports Medicine**

[0094] Treating all muscle groups prior to
training will increase the level to which the athlete can
train by as much as 50%, in addition to decreasing the
incidence of muscle injury.

[0095] In a double blind trial, five volunteers
were used by treating one limb with placebo radiation and the
corresponding other limb with active radiation. In all cases
the volunteers were able to increase their effort tolerance
before feeling muscle fatigue by 30-50% in the limb treated
with the active radiation.

[0096] Muscle injuries have been successfully
treated in 35 patients. The pathology involved included rotor
cuff syndrome, tennis elbow, lower back pain and lumbar
fascitis. The response to therapy ranged from immediate relief
in 30% of cases to complete relief after 24 hours in the
remaining 70%. Daily treatment is required until the problem
is resolved.

**Ophthalmic Conditions**

[0097] Chronic ophthalmic pain was successfully
alleviated permanently in 90% of the eleven patients treated.

[0098] Unstable corneal epithelium (over a
period of 6 weeks) which resulted in recurrent corneal
ulceration, was stabilised in 6 patients promoting an intact
corneal surface within 5 days of commencement of daily
treatments of radiation therapy.

[0099] Four patients with conjunctivitis sicca
or dry eye syndrome, reported significantly decreased eye
irritation and produced significantly less debris accumulation
within fornices following radiation treatment. Of note was the
experience that whilst radiation centred on 1072 nm was
effective in this condition, radiation centred on 1268 nm was
more effective. Once weekly treatment with radiation was
sufficient to alleviate symptoms.

[0100] Episcleritis and other inflammatory
conditions of the eye were successfully treated in 11
patients. Daily treatments were necessary to obtain the
desired clinical effect. The recurrence of the inflammatory
condition was decreased in all cases. All patients treated had
suffered their conditions over several months and resolution
occurred in 3-4 days without the use of eye drops.

[0101] Severe caustic injury to the eye is
considered untreatable and almost always results in
destruction of the cornea and blindness. Animal experiments
(conducted in South Africa) have indicated that caustic injury
is treatable with the radiation of the present invention.

[0102] Five pairs of rabbit eyes were exposed to
a supersaturated solution of NaOH for 30 seconds after topical
administration of an anaesthetic. All eyes were washed out
thoroughly following the caustic injury and it was noted that
the corneas were immediately opaque following the injury. One
eye of each rabbit was then either treated with conventional
steroids plus antibiotic whilst the other eye was treated with
the radiation of the present invention. All rabbits were
sacrificed 4 weeks following twice daily treatment. In all
cases the eyes that had been treated with conventional therapy
(steroids plus antibiotic) rapidly developed panophthalmilitis
with resulting blindness, whilst the eyes treated with the
radiation therapy of the invention showed that the anterior
chamber, lens, vitreous and retina were intact despite corneal
damage. In addition the scar tissue in the radiation treated
eyes was reduced by at least 50% compared to the
conventionally treated eyes.

[0103] Further experiments involving a less
concentrated solution of NaOH being applied for a longer
duration, 3 minutes, resulted in corneal damage to all eyes as
gauged by pale milky appearance to the corneas. The same
protocol of treatment was applied, I.E. one eye being treated
in conventional manner and the other by radiation therapy. The
animal were sacrificed following two weeks of treatment and
the results showed that eyes treated with the radiation
therapy were clear whilst the conventionally treated eyes
remained opaque.

[0104] The ability to reduce scarring was
investigated using 5 pairs of rabbit eyes. Each eye was
scarred by a 4 mm linear full thickness incision in the centre
of the corneas under topical anaesthesia. One eye was treated
conventionally and the other by radiation therapy. All eyes
healed however the eyes receiving radiation therapy healed at
a faster rate with scarring reduced by 50%. It was noted that
radiation centred on 1072 nm gave best similar results.

**Pain**

[0105] Radiation at 950 nm was only marginally
effective compared to the restricted radiation at 1072 and
1268 nm. It was noted that 1072 nm was more effective than
1268 nm radiation in treatment of acute pain as caused by a
superficial burn However, 1268 nm radiation was reported as
more effective at alleviating deep muscle pain caused by
muscle injury.

[0106] Pain was gauged in patients by subjective
assessment.

[0107] Thus it will be appreciated that the
radiation therapy system of the present invention has wide
application in treating a variety of different diseases and
conditions. The radiation therapy system effects on a patient
are rapidly felt and since the system is non-invasive it
presents a less stressful/traumatic therapy to the patient.
Moreover, the system could be used to treat a wide variety of
patients quickly thus reducing the financial burden to the
health service.

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